Morphine Sulfate
GENERIC NAME
Morphine Sulfate
TRADE NAME
Morphine
DESCRIPTION
Morphine Sulfate is an opioid pain reliever used to manage moderate to severe pain. It acts as a central nervous system depressant, providing both analgesia and sedation.
HOW SUPPLIED
Ampule and multi-dose vial: 10 mg/1 ml
INDICATIONS
- Patients with pain of non-traumatic origin
- Burn patients with pain
- Analgesia prior to cardioversion
CONTRAINDICATIONS
- Allergy or hypersensitivity to Morphine
- Should not be used in trauma patients (other than burn injuries)
- Undiagnosed head injury or sudden onset of altered mental status
MECHANISM OF ACTION
Morphine Sulfate acts as a central nervous system depressant, providing pain relief and sedation by binding to opioid receptors in the brain and spinal cord.
SIDE EFFECTS
- Nausea
- Vomiting
- Abdominal cramps
- Blurred vision
- Constricted pupils
- Altered mental status
- Headache
- Respiratory depression
AUTHORIZATION
Paramedic: Standing order and Medical Control
DOSAGE
| Patient Type | Route | Standard Dosage | Maximum Dosage |
|---|---|---|---|
| Adult (Non-burn pain) | IV/IO/IM | 2–5 mg slow push | 10 mg total |
| Adult (Burn patients) | IV/IO/IM | 2–5 mg slow push | 20 mg total |
| Pediatric (Non-burn pain) | IV/IO/IM | 0.1 mg/kg slow push | 5 mg total |
| Pediatric (Burn patients) | IV/IO/IM | 0.1 mg/kg slow push | 10 mg total |
Administration Notes:
- Administer Morphine slowly over several minutes to avoid rapid onset of side effects, particularly respiratory depression.
- Monitor respiratory status closely, especially in patients with underlying respiratory conditions.
- For burn patients, higher maximum dosages are permitted due to the severity of pain.