# Morphine Sulfate

#### **GENERIC NAME**

#### Morphine Sulfate

#### **TRADE NAME**

#### Morphine

#### **DESCRIPTION**

Morphine Sulfate is an opioid pain reliever used to manage moderate to severe pain. It acts as a central nervous system depressant, providing both analgesia and sedation.

#### **HOW SUPPLIED**

Ampule and multi-dose vial: 10 mg/1 ml

#### **INDICATIONS**

- Patients with pain of non-traumatic origin
- Burn patients with pain
- Analgesia prior to cardioversion

#### **CONTRAINDICATIONS**

- Allergy or hypersensitivity to Morphine
- Should not be used in trauma patients (other than burn injuries)
- Undiagnosed head injury or sudden onset of altered mental status

#### **MECHANISM OF ACTION**

Morphine Sulfate acts as a central nervous system depressant, providing pain relief and sedation by binding to opioid receptors in the brain and spinal cord.

#### **SIDE EFFECTS**

- Nausea
- Vomiting
- Abdominal cramps
- Blurred vision
- Constricted pupils
- Altered mental status
- Headache
- Respiratory depression

#### **AUTHORIZATION**

**EMT:** Not authorized

**AEMT:** Not authorized

**Paramedic:** Standing order and Medical Control

#### **DOSAGE**

<table border="1" id="bkmrk-patient-type-route-s"><tbody><tr><th>Patient Type</th><th>Route</th><th>Standard Dosage</th><th>Maximum Dosage</th></tr><tr><td>Adult (Non-burn pain)</td><td>IV/IO/IM</td><td>2–5 mg slow push</td><td>10 mg total</td></tr><tr><td>Adult (Burn patients)</td><td>IV/IO/IM</td><td>2–5 mg slow push</td><td>20 mg total</td></tr><tr><td>Pediatric (Non-burn pain)</td><td>IV/IO/IM</td><td>0.1 mg/kg slow push</td><td>5 mg total</td></tr><tr><td>Pediatric (Burn patients)</td><td>IV/IO/IM</td><td>0.1 mg/kg slow push</td><td>10 mg total</td></tr></tbody></table>

##### **Administration Notes:**

- Administer Morphine slowly over several minutes to avoid rapid onset of side effects, particularly respiratory depression.
- Monitor respiratory status closely, especially in patients with underlying respiratory conditions.
- For burn patients, higher maximum dosages are permitted due to the severity of pain.